PQQ ameliorates D-galactose induced cognitive impairments by reducing glutamate neurotoxicity via the GSK-3β/Akt signaling pathway in mouse

Oxidative stress is known to be associated with various age-related diseases. D-galactose (D-gal) has been considered a senescent model which induces oxidative stress response resulting in memory dysfunction. Pyrroloquinoline quinone (PQQ) is a redox cofactor which is found in various foods. In our...

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Detalles Bibliográficos
Autores principales: Zhou, Xing-qin, Yao, Zhi-wen, Peng, Ying, Mao, Shi-shi, Xu, Dong, Qin, Xiao-feng, Zhang, Rong-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995849/
https://www.ncbi.nlm.nih.gov/pubmed/29891841
http://dx.doi.org/10.1038/s41598-018-26962-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995849/
https://www.ncbi.nlm.nih.gov/pubmed/29891841
http://dx.doi.org/10.1038/s41598-018-26962-9

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