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Postsynaptic RIM1 modulates synaptic function by facilitating membrane delivery of recycling NMDARs in hippocampal neurons

NMDA receptors (NMDARs) are crucial for excitatory synaptic transmission and synaptic plasticity. The number and subunit composition of synaptic NMDARs are tightly controlled by neuronal activity and sensory experience, but the molecular mechanism mediating NMDAR trafficking remains poorly understoo...

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Detalles Bibliográficos
Autores principales: Wang, Jiejie, Lv, Xinyou, Wu, Yu, Xu, Tao, Jiao, Mingfei, Yang, Risheng, Li, Xia, Chen, Ming, Yan, Yinggang, Chen, Changwan, Dong, Weifan, Yang, Wei, Zhuo, Min, Chen, Tao, Luo, Jianhong, Qiu, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995852/
https://www.ncbi.nlm.nih.gov/pubmed/29891949
http://dx.doi.org/10.1038/s41467-018-04672-0