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Diverse antimalarials from whole-cell phenotypic screens disrupt malaria parasite ion and volume homeostasis
Four hundred structurally diverse drug-like compounds comprising the Medicines for Malaria Venture’s ‘Pathogen Box’ were screened for their effect on a range of physiological parameters in asexual blood-stage malaria (Plasmodium falciparum) parasites. Eleven of these compounds were found to perturb...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995868/ https://www.ncbi.nlm.nih.gov/pubmed/29892073 http://dx.doi.org/10.1038/s41598-018-26819-1 |