Prostate-Specific Membrane Antigen-Targeted Site-Directed Antibody-Conjugated Apoferritin Nanovehicle Favorably Influences In Vivo Side Effects of Doxorubicin

Herein, we describe the in vivo effects of doxorubicin (DOX) encapsulated in ubiquitous protein apoferritin (APO) and its efficiency and safety in anti-tumor treatment. APODOX is both passively (through Enhanced Permeability and Retention effect) and actively targeted to tumors through prostate-spec...

Descripción completa

Detalles Bibliográficos
Autores principales: Dostalova, Simona, Polanska, Hana, Svobodova, Marketa, Balvan, Jan, Krystofova, Olga, Haddad, Yazan, Krizkova, Sona, Masarik, Michal, Eckschlager, Tomas, Stiborova, Marie, Heger, Zbynek, Adam, Vojtech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995913/
https://www.ncbi.nlm.nih.gov/pubmed/29891921
http://dx.doi.org/10.1038/s41598-018-26772-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995913/
https://www.ncbi.nlm.nih.gov/pubmed/29891921
http://dx.doi.org/10.1038/s41598-018-26772-z

Ejemplares similares