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Prostate-Specific Membrane Antigen-Targeted Site-Directed Antibody-Conjugated Apoferritin Nanovehicle Favorably Influences In Vivo Side Effects of Doxorubicin
Herein, we describe the in vivo effects of doxorubicin (DOX) encapsulated in ubiquitous protein apoferritin (APO) and its efficiency and safety in anti-tumor treatment. APODOX is both passively (through Enhanced Permeability and Retention effect) and actively targeted to tumors through prostate-spec...
Autores principales: | Dostalova, Simona, Polanska, Hana, Svobodova, Marketa, Balvan, Jan, Krystofova, Olga, Haddad, Yazan, Krizkova, Sona, Masarik, Michal, Eckschlager, Tomas, Stiborova, Marie, Heger, Zbynek, Adam, Vojtech |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995913/ https://www.ncbi.nlm.nih.gov/pubmed/29891921 http://dx.doi.org/10.1038/s41598-018-26772-z |
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