Soluble E-cadherin promotes tumor angiogenesis and localizes to exosome surface

The limitations of current anti-angiogenic therapies necessitate other targets with complimentary mechanisms. Here, we show for the first time that soluble E-cadherin (sE-cad) (an 80-kDa soluble form), which is highly expressed in the malignant ascites of ovarian cancer patients, is a potent inducer...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Maggie K. S., Yue, Patrick Y. K., Ip, Philip P., Huang, Rui-Lan, Lai, Hung-Cheng, Cheung, Annie N. Y., Tse, Ka Yu, Ngan, Hextan Y. S., Wong, Alice S. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995921/
https://www.ncbi.nlm.nih.gov/pubmed/29891938
http://dx.doi.org/10.1038/s41467-018-04695-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995921/
https://www.ncbi.nlm.nih.gov/pubmed/29891938
http://dx.doi.org/10.1038/s41467-018-04695-7

Ejemplares similares