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Soluble E-cadherin promotes tumor angiogenesis and localizes to exosome surface

The limitations of current anti-angiogenic therapies necessitate other targets with complimentary mechanisms. Here, we show for the first time that soluble E-cadherin (sE-cad) (an 80-kDa soluble form), which is highly expressed in the malignant ascites of ovarian cancer patients, is a potent inducer...

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Detalles Bibliográficos
Autores principales:	Tang, Maggie K. S., Yue, Patrick Y. K., Ip, Philip P., Huang, Rui-Lan, Lai, Hung-Cheng, Cheung, Annie N. Y., Tse, Ka Yu, Ngan, Hextan Y. S., Wong, Alice S. T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995921/ https://www.ncbi.nlm.nih.gov/pubmed/29891938 http://dx.doi.org/10.1038/s41467-018-04695-7

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