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Airway brushing as a new experimental methodology to detect airway gene expression signatures in mouse lung squamous cell carcinoma

As a consequence of exposure to environmental toxicants, a “field cancerization” effect occurs in the lung, resulting in the development of a field of initiated, but morphologically normal appearing cells within a damaged epithelium containing mutations in oncogene or tumor suppressor genes. Unlike...

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Detalles Bibliográficos
Autores principales: Pan, Jing, Xiong, Donghai, Zhang, Qi, Szabo, Eva, Miller, Mark Steven, Lubet, Ronald A., Wang, Yian, You, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995924/
https://www.ncbi.nlm.nih.gov/pubmed/29891994
http://dx.doi.org/10.1038/s41598-018-26902-7