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Airway brushing as a new experimental methodology to detect airway gene expression signatures in mouse lung squamous cell carcinoma
As a consequence of exposure to environmental toxicants, a “field cancerization” effect occurs in the lung, resulting in the development of a field of initiated, but morphologically normal appearing cells within a damaged epithelium containing mutations in oncogene or tumor suppressor genes. Unlike...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995924/ https://www.ncbi.nlm.nih.gov/pubmed/29891994 http://dx.doi.org/10.1038/s41598-018-26902-7 |