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A Nasal Brush-based Classifier of Asthma Identified by Machine Learning Analysis of Nasal RNA Sequence Data

Asthma is a common, under-diagnosed disease affecting all ages. We sought to identify a nasal brush-based classifier of mild/moderate asthma. 190 subjects with mild/moderate asthma and controls underwent nasal brushing and RNA sequencing of nasal samples. A machine learning-based pipeline identified...

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Detalles Bibliográficos
Autores principales: Pandey, Gaurav, Pandey, Om P., Rogers, Angela J., Ahsen, Mehmet E., Hoffman, Gabriel E., Raby, Benjamin A., Weiss, Scott T., Schadt, Eric E., Bunyavanich, Supinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995932/
https://www.ncbi.nlm.nih.gov/pubmed/29891868
http://dx.doi.org/10.1038/s41598-018-27189-4