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Aberrant DNA methylation of the p16, APC, MGMT, TIMP3 and CDH1 gene promoters in tumours and the surgical margins of patients with oral cavity cancer

Oral cavity cancer is a type of head and neck squamous cell carcinoma (HNSCC) and contributes to significant morbidity and mortality each year. An epigenetic pathway of transcriptional inactivation for many genes has been described in various cancers, including HNSCC. For our study, we selected gene...

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Detalles Bibliográficos
Autores principales: Strzelczyk, Joanna Katarzyna, Krakowczyk, Łukasz, Owczarek, Aleksander Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995944/
https://www.ncbi.nlm.nih.gov/pubmed/29896273
http://dx.doi.org/10.7150/jca.24477