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Distinct Immunomodulatory Effects of Spermine Oxidase in Colitis Induced by Epithelial Injury or Infection

Polyamines have been implicated in numerous biological processes, including inflammation and carcinogenesis. Homeostatic regulation leads to interconversion of the polyamines putrescine and the downstream metabolites spermidine and spermine. The enzyme spermine oxidase (SMOX), which back-converts sp...

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Detalles Bibliográficos
Autores principales: Gobert, Alain P., Al-Greene, Nicole T., Singh, Kshipra, Coburn, Lori A., Sierra, Johanna C., Verriere, Thomas G., Luis, Paula B., Schneider, Claus, Asim, Mohammad, Allaman, Margaret M., Barry, Daniel P., Cleveland, John L., Destefano Shields, Christina E., Casero, Robert A., Washington, M. Kay, Piazuelo, M. Blanca, Wilson, Keith T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996034/
https://www.ncbi.nlm.nih.gov/pubmed/29922289
http://dx.doi.org/10.3389/fimmu.2018.01242