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Distinct Immunomodulatory Effects of Spermine Oxidase in Colitis Induced by Epithelial Injury or Infection
Polyamines have been implicated in numerous biological processes, including inflammation and carcinogenesis. Homeostatic regulation leads to interconversion of the polyamines putrescine and the downstream metabolites spermidine and spermine. The enzyme spermine oxidase (SMOX), which back-converts sp...
Autores principales: | Gobert, Alain P., Al-Greene, Nicole T., Singh, Kshipra, Coburn, Lori A., Sierra, Johanna C., Verriere, Thomas G., Luis, Paula B., Schneider, Claus, Asim, Mohammad, Allaman, Margaret M., Barry, Daniel P., Cleveland, John L., Destefano Shields, Christina E., Casero, Robert A., Washington, M. Kay, Piazuelo, M. Blanca, Wilson, Keith T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996034/ https://www.ncbi.nlm.nih.gov/pubmed/29922289 http://dx.doi.org/10.3389/fimmu.2018.01242 |
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