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Promyelocytic Leukemia Restricts Enterovirus 71 Replication by Inhibiting Autophagy

The promyelocytic leukemia (PML) protein, also known as TRIM19, functions as a major organizer of PML nuclear bodies (NBs) in most mammalian cells and plays important roles in antiviral activities against both DNA and RNA viruses. In this study, we found that the downregulation of PML rendered HeLa...

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Detalles Bibliográficos
Autores principales: Chen, Deyan, Feng, Chunhong, Tian, Xiaoyan, Zheng, Nan, Wu, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996053/
https://www.ncbi.nlm.nih.gov/pubmed/29922292
http://dx.doi.org/10.3389/fimmu.2018.01268