T Cell Receptor–Major Histocompatibility Complex Interaction Strength Defines Trafficking and CD103(+) Memory Status of CD8 T Cells in the Brain

T cell receptor–major histocompatibility complex (TCR–MHC) affinities span a wide range in a polyclonal T cell response, yet it is undefined how affinity shapes long-term properties of CD8 T cells during chronic infection with persistent antigen. Here, we investigate how the affinity of the TCR–MHC...

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Detalles Bibliográficos
Autores principales: Sanecka, Anna, Yoshida, Nagisa, Kolawole, Elizabeth Motunrayo, Patel, Harshil, Evavold, Brian D., Frickel, Eva-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996069/
https://www.ncbi.nlm.nih.gov/pubmed/29922298
http://dx.doi.org/10.3389/fimmu.2018.01290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996069/
https://www.ncbi.nlm.nih.gov/pubmed/29922298
http://dx.doi.org/10.3389/fimmu.2018.01290

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