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Using Gene Expression to Annotate Cardiovascular GWAS Loci

Genetic variants at hundreds of loci associated with cardiovascular phenotypes have been identified by genome wide association studies. Most of these variants are located in intronic or intergenic regions rendering the functional and mechanistic follow up difficult. These non-protein-coding regions...

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Detalles Bibliográficos
Autor principal: Heinig, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996083/
https://www.ncbi.nlm.nih.gov/pubmed/29922679
http://dx.doi.org/10.3389/fcvm.2018.00059