Partial Depletion of Peripheral M1 Macrophages Reverses Motor Deficits in MPTP-Treated Mouse by Suppressing Neuroinflammation and Dopaminergic Neurodegeneration

Background: Neuroinflammation plays an important role in the pathogenesis of Parkinson's disease (PD). Inflammatory cytokines in the peripheral immune system can induce neuroinflammation in central nervous system (CNS). Whether the peripheral immune system is involved in PD is unclear. The pres...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Aijuan, Zhang, Yu, Lin, Jingya, Song, Lu, Wang, Xijin, Liu, Zhenguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996129/
https://www.ncbi.nlm.nih.gov/pubmed/29922149
http://dx.doi.org/10.3389/fnagi.2018.00160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996129/
https://www.ncbi.nlm.nih.gov/pubmed/29922149
http://dx.doi.org/10.3389/fnagi.2018.00160

Ejemplares similares