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Dysregulation of 5-hydroxytryptamine 6 receptor accelerates maturation of bone-resorbing osteoclasts and induces bone loss

Rationale: Characterizing the regulation of bone-resorbing osteoclasts is central to the understanding of the pathogenesis and treatment of bone diseases, such as osteoporosis and periodontitis. 5-hydroxytryptamine (5-HT) has drawn considerable attention for its role in bone; however, it remains unk...

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Detalles Bibliográficos
Autores principales: Park, Kyung-Ran, Kim, Eun-Cheol, Hong, Jin Tae, Yun, Hyung-Mun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996355/
https://www.ncbi.nlm.nih.gov/pubmed/29896304
http://dx.doi.org/10.7150/thno.24426