Flow-dependent epigenetic regulation of IGFBP5 expression by H3K27me3 contributes to endothelial anti-inflammatory effects

Rationale: Atherosclerosis is a chronic inflammatory and epigenetic disease that is influenced by different patterns of blood flow. However, the epigenetic mechanism whereby atheroprotective flow controls endothelial gene programming remains elusive. Here, we investigated the possibility that flow a...

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Detalles Bibliográficos
Autores principales: Xu, Suowen, Xu, Yanni, Yin, Meimei, Zhang, Shuya, Liu, Peng, Koroleva, Marina, Si, Shuyi, Little, Peter J., Pelisek, Jaroslav, Jin, Zheng Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996356/
https://www.ncbi.nlm.nih.gov/pubmed/29896299
http://dx.doi.org/10.7150/thno.21966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996356/
https://www.ncbi.nlm.nih.gov/pubmed/29896299
http://dx.doi.org/10.7150/thno.21966

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