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The Transcription Factor ATF4 Promotes Expression of Cell Stress Genes and Cardiomyocyte Death in a Cellular Model of Atrial Fibrillation

INTRODUCTION: Cardiomyocyte remodelling in atrial fibrillation (AF) has been associated with both oxidative stress and endoplasmic reticulum (ER) stress and is accompanied by a complex transcriptional regulation. Here, we investigated the role the oxidative stress and ER stress responsive bZIP trans...

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Detalles Bibliográficos
Autores principales: Freundt, Johanna K., Frommeyer, Gerrit, Wötzel, Fabian, Huge, Andreas, Hoffmeier, Andreas, Martens, Sven, Eckardt, Lars, Lange, Philipp S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996409/
https://www.ncbi.nlm.nih.gov/pubmed/30003094
http://dx.doi.org/10.1155/2018/3694362