A Profibrotic Phenotype in Naïve and in Fibrotic Lung Myofibroblasts Is Governed by Modulations in Thy-1 Expression and Activation

Lung fibrosis is characterized by abnormal accumulation of Thy-deficient fibroblasts in the interstitium of the alveolar space. We have previously shown in bleomycin-treated chimeric Thy1-deficient mice with wild-type lymphocytes that Thy1-deficient fibroblasts accumulate and promote fibrosis and an...

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Detalles Bibliográficos
Autores principales: Cohen, Pazit Y., Breuer, Raphael, Wallach-Dayan, Shulamit B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996423/
https://www.ncbi.nlm.nih.gov/pubmed/30002599
http://dx.doi.org/10.1155/2018/4638437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996423/
https://www.ncbi.nlm.nih.gov/pubmed/30002599
http://dx.doi.org/10.1155/2018/4638437

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