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27nt-RNAs guide histone variant deposition via ‘RNA-induced DNA replication interference’ and thus transmit parental genome partitioning in Stylonychia

BACKGROUND: During sexual reproduction in the unicellular ciliate Stylonychia somatic macronuclei differentiate from germline micronuclei. Thereby, programmed sequence reduction takes place, leading to the elimination of > 95% of germline sequences, which priorly adopt heterochromatin structure v...

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Detalles Bibliográficos
Autores principales: Postberg, Jan, Jönsson, Franziska, Weil, Patrick Philipp, Bulic, Aneta, Juranek, Stefan Andreas, Lipps, Hans-Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996456/
https://www.ncbi.nlm.nih.gov/pubmed/29895326
http://dx.doi.org/10.1186/s13072-018-0201-5