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Complement C5a Alters the Membrane Potential of Neutrophils during Hemorrhagic Shock

BACKGROUND: Polymorphonuclear granulocytes (PMN) play a crucial role in host defense. Physiologically, exposure of PMN to the complement activation product C5a results in a protective response against pathogens, whereas in the case of systemic inflammation, excessive C5a substantially impairs neutro...

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Detalles Bibliográficos
Autores principales: Messerer, David A. C., Denk, Stephanie, Föhr, Karl J., Halbgebauer, Rebecca, Braun, Christian K., Hönes, Felix, Harant, Julia, Fauler, Michael, Frick, Manfred, Nußbaum, Benedikt L., Radermacher, Peter, Hafner, Sebastian, Huber-Lang, Markus S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996468/
https://www.ncbi.nlm.nih.gov/pubmed/30002598
http://dx.doi.org/10.1155/2018/2052356