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Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy

BACKGROUND: Corticosteroids are routinely utilized to alleviate edema in patients with intracranial lesions and are first-line agents to combat immune-related adverse events (irAEs) that arise with immune checkpoint blockade treatment. However, it is not known if or when corticosteroids can be admin...

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Detalles Bibliográficos
Autores principales: Giles, Amber J., Hutchinson, Marsha-Kay N. D., Sonnemann, Heather M., Jung, Jinkyu, Fecci, Peter E., Ratnam, Nivedita M., Zhang, Wei, Song, Hua, Bailey, Rolanda, Davis, Dionne, Reid, Caitlin M., Park, Deric M., Gilbert, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996496/
https://www.ncbi.nlm.nih.gov/pubmed/29891009
http://dx.doi.org/10.1186/s40425-018-0371-5