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PAPP-A2 deficiency does not exacerbate the phenotype of a mouse model of intrauterine growth restriction

BACKGROUND: Pregnancy-associated plasma protein-A2 (PAPP-A2) is consistently upregulated in the placentae of pregnancies complicated by preeclampsia and fetal growth restriction. The causes and significance of this upregulation remain unknown, but it has been hypothesized that it is a compensatory r...

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Detalles Bibliográficos
Autores principales: Christians, Julian K., Lennie, Kendra I., Huicochea Munoz, Maria F., Binning, Nimrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996520/
https://www.ncbi.nlm.nih.gov/pubmed/29895300
http://dx.doi.org/10.1186/s12958-018-0376-4