PYNOD reduces microglial inflammation and consequent neurotoxicity upon lipopolysaccharides stimulation

PYNOD, a nod-like receptors (NLR)-like protein, was indicated to inhibit NF-κB activation, caspase-1-mediated interleukin (IL)-1β release and cell apoptosis in a dose-dependent manner. Exogenous addition of recombinant PYNOD to mixed glial cultures may suppress caspase-1 activation and IL-1β secreti...

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Detalles Bibliográficos
Autores principales: Zeng, Qi, Hu, Chaofeng, Qi, Renbin, Lu, Daxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996706/
https://www.ncbi.nlm.nih.gov/pubmed/29904414
http://dx.doi.org/10.3892/etm.2018.6108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996706/
https://www.ncbi.nlm.nih.gov/pubmed/29904414
http://dx.doi.org/10.3892/etm.2018.6108

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