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Overlap between age-at-onset and disease-progression determinants in Huntington disease

OBJECTIVE: A fundamental but still unresolved issue regarding Huntington disease (HD) pathogenesis is whether the factors that determine age at onset are the same as those that govern disease progression. Because elucidation of this issue is crucial for the development as well as optimal timing of a...

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Detalles Bibliográficos
Autores principales: Aziz, N. Ahmad, van der Burg, Jorien M.M., Tabrizi, Sarah J., Landwehrmeyer, G. Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996832/
https://www.ncbi.nlm.nih.gov/pubmed/29743208
http://dx.doi.org/10.1212/WNL.0000000000005690