Cargando…
Overlap between age-at-onset and disease-progression determinants in Huntington disease
OBJECTIVE: A fundamental but still unresolved issue regarding Huntington disease (HD) pathogenesis is whether the factors that determine age at onset are the same as those that govern disease progression. Because elucidation of this issue is crucial for the development as well as optimal timing of a...
Autores principales: | Aziz, N. Ahmad, van der Burg, Jorien M.M., Tabrizi, Sarah J., Landwehrmeyer, G. Bernhard |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996832/ https://www.ncbi.nlm.nih.gov/pubmed/29743208 http://dx.doi.org/10.1212/WNL.0000000000005690 |
Ejemplares similares
-
Effect of Body Weight on Age at Onset in Huntington Disease: A Mendelian Randomization Study
por: van der Burg, Jorien M.M., et al.
Publicado: (2021) -
Observing Huntington’s Disease: the European Huntington’s Disease Network’s REGISTRY
por: Orth, Michael, et al.
Publicado: (2011) -
The gene coding for PGC-1α modifies age at onset in Huntington's Disease
por: Weydt, Patrick, et al.
Publicado: (2009) -
Progressive alterations in white matter microstructure across the timecourse of Huntington's disease
por: Estevez‐Fraga, Carlos, et al.
Publicado: (2023) -
Disease Onset in Huntington's Disease: When Is the Conversion?
por: Oosterloo, Mayke, et al.
Publicado: (2021)