Modeling Keratoconus Using Induced Pluripotent Stem Cells

PURPOSE: To model keratoconus (KC) using induced pluripotent stem cells (iPSC) generated from fibroblasts of both KC and normal human corneal stroma by a viral method. METHODS: Both normal and KC corneal fibroblasts from four human donors were reprogramed directly by delivering reprogramming factors...

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Detalles Bibliográficos
Autores principales: Joseph, Roy, Srivastava, Om P., Pfister, Roswell R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996875/
https://www.ncbi.nlm.nih.gov/pubmed/27403997
http://dx.doi.org/10.1167/iovs.16-19105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996875/
https://www.ncbi.nlm.nih.gov/pubmed/27403997
http://dx.doi.org/10.1167/iovs.16-19105

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