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Modeling Keratoconus Using Induced Pluripotent Stem Cells

PURPOSE: To model keratoconus (KC) using induced pluripotent stem cells (iPSC) generated from fibroblasts of both KC and normal human corneal stroma by a viral method. METHODS: Both normal and KC corneal fibroblasts from four human donors were reprogramed directly by delivering reprogramming factors...

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Detalles Bibliográficos
Autores principales:	Joseph, Roy, Srivastava, Om P., Pfister, Roswell R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2016
Materias:	Cornea
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996875/ https://www.ncbi.nlm.nih.gov/pubmed/27403997 http://dx.doi.org/10.1167/iovs.16-19105

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