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Alpha-1 Antitrypsin Inhibits ATP-Mediated Release of Interleukin-1β via CD36 and Nicotinic Acetylcholine Receptors

While interleukin (IL)-1β is a potent pro-inflammatory cytokine involved in host defense, high levels can cause life-threatening sterile inflammation including systemic inflammatory response syndrome. Hence, the control of IL-1β secretion is of outstanding biomedical importance. In response to a fir...

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Detalles Bibliográficos
Autores principales: Siebers, Kathrin, Fink, Bijan, Zakrzewicz, Anna, Agné, Alisa, Richter, Katrin, Konzok, Sebastian, Hecker, Andreas, Zukunft, Sven, Küllmar, Mira, Klein, Jochen, McIntosh, J. Michael, Timm, Thomas, Sewald, Katherina, Padberg, Winfried, Aggarwal, Nupur, Chamulitrat, Walee, Santoso, Sentot, Xia, Wendy, Janciauskiene, Sabina, Grau, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996888/
https://www.ncbi.nlm.nih.gov/pubmed/29922281
http://dx.doi.org/10.3389/fimmu.2018.00877