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Primary Human Microglia Are Phagocytically Active and Respond to Borrelia burgdorferi With Upregulation of Chemokines and Cytokines

The Lyme disease causing bacterium Borrelia burgdorferi has an affinity for the central nervous system (CNS) and has been isolated from human cerebral spinal fluid by 18 days following Ixodes scapularis tick bite. Signaling from resident immune cells of the CNS could enhance CNS penetration by B. bu...

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Detalles Bibliográficos
Autores principales: Greenmyer, Jacob R., Gaultney, Robert A., Brissette, Catherine A., Watt, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996889/
https://www.ncbi.nlm.nih.gov/pubmed/29922241
http://dx.doi.org/10.3389/fmicb.2018.00811