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Cord Blood CD8(+) T Cells Have a Natural Propensity to Express IL-4 in a Fatty Acid Metabolism and Caspase Activation-Dependent Manner

How T cells differentiate in the neonate may critically determine the ability of the infant to cope with infections, respond to vaccines and avert allergies. Previously, we found that naïve cord blood CD4(+) T cells differentiated toward an IL-4-expressing phenotype when activated in the presence of...

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Detalles Bibliográficos
Autores principales: Zhang, Yuxia, Maksimovic, Jovana, Huang, Bing, De Souza, David Peter, Naselli, Gaetano, Chen, Huan, Zhang, Li, Weng, Kai, Liang, Hanquan, Xu, Yanhui, Wentworth, John M., Huntington, Nicholas D., Oshlack, Alicia, Gong, Sitang, Kallies, Axel, Vuillermin, Peter, Yang, Min, Harrison, Leonard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996926/
https://www.ncbi.nlm.nih.gov/pubmed/29922282
http://dx.doi.org/10.3389/fimmu.2018.00879