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A role for the Smc3 hinge domain in the maintenance of sister chromatid cohesion

Cohesin is a conserved protein complex required for sister chromatid cohesion, chromosome condensation, DNA damage repair, and regulation of transcription. Although cohesin functions to tether DNA duplexes, the contribution of its individual domains to this activity remains poorly understood. We int...

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Detalles Bibliográficos
Autores principales: Robison, Brett, Guacci, Vincent, Koshland, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996953/
https://www.ncbi.nlm.nih.gov/pubmed/29187575
http://dx.doi.org/10.1091/mbc.E17-08-0511