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A role for the Smc3 hinge domain in the maintenance of sister chromatid cohesion
Cohesin is a conserved protein complex required for sister chromatid cohesion, chromosome condensation, DNA damage repair, and regulation of transcription. Although cohesin functions to tether DNA duplexes, the contribution of its individual domains to this activity remains poorly understood. We int...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996953/ https://www.ncbi.nlm.nih.gov/pubmed/29187575 http://dx.doi.org/10.1091/mbc.E17-08-0511 |