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Stu2 uses a 15-nm parallel coiled coil for kinetochore localization and concomitant regulation of the mitotic spindle

XMAP215/Dis1 family proteins are potent microtubule polymerases, critical for mitotic spindle structure and dynamics. While microtubule polymerase activity is driven by an N-terminal tumor overexpressed gene (TOG) domain array, proper cellular localization is a requisite for full activity and is med...

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Detalles Bibliográficos
Autores principales: Haase, Karen P., Fox, Jaime C., Byrnes, Amy E., Adikes, Rebecca C., Speed, Sarah K., Haase, Julian, Friedman, Brandon, Cook, Diana M., Bloom, Kerry, Rusan, Nasser M., Slep, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996958/
https://www.ncbi.nlm.nih.gov/pubmed/29187574
http://dx.doi.org/10.1091/mbc.E17-01-0057