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Stu2 uses a 15-nm parallel coiled coil for kinetochore localization and concomitant regulation of the mitotic spindle
XMAP215/Dis1 family proteins are potent microtubule polymerases, critical for mitotic spindle structure and dynamics. While microtubule polymerase activity is driven by an N-terminal tumor overexpressed gene (TOG) domain array, proper cellular localization is a requisite for full activity and is med...
Autores principales: | Haase, Karen P., Fox, Jaime C., Byrnes, Amy E., Adikes, Rebecca C., Speed, Sarah K., Haase, Julian, Friedman, Brandon, Cook, Diana M., Bloom, Kerry, Rusan, Nasser M., Slep, Kevin C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996958/ https://www.ncbi.nlm.nih.gov/pubmed/29187574 http://dx.doi.org/10.1091/mbc.E17-01-0057 |
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