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Host cell perforation by listeriolysin O (LLO) activates a Ca(2+)-dependent cPKC/Rac1/Arp2/3 signaling pathway that promotes Listeria monocytogenes internalization independently of membrane resealing

Host cell invasion is an indispensable step for a successful infection by intracellular pathogens. Recent studies identified pathogen-induced host cell plasma membrane perforation as a novel mechanism used by diverse pathogens (Trypanosoma cruzi, Listeria monocytogenes, and adenovirus) to promote th...

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Detalles Bibliográficos
Autores principales: Lam, Jonathan G. T., Vadia, Stephen, Pathak-Sharma, Sarika, McLaughlin, Eric, Zhang, Xiaoli, Swanson, Joel, Seveau, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996962/
https://www.ncbi.nlm.nih.gov/pubmed/29187576
http://dx.doi.org/10.1091/mbc.E17-09-0561