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Host cell perforation by listeriolysin O (LLO) activates a Ca(2+)-dependent cPKC/Rac1/Arp2/3 signaling pathway that promotes Listeria monocytogenes internalization independently of membrane resealing
Host cell invasion is an indispensable step for a successful infection by intracellular pathogens. Recent studies identified pathogen-induced host cell plasma membrane perforation as a novel mechanism used by diverse pathogens (Trypanosoma cruzi, Listeria monocytogenes, and adenovirus) to promote th...
Autores principales: | Lam, Jonathan G. T., Vadia, Stephen, Pathak-Sharma, Sarika, McLaughlin, Eric, Zhang, Xiaoli, Swanson, Joel, Seveau, Stephanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996962/ https://www.ncbi.nlm.nih.gov/pubmed/29187576 http://dx.doi.org/10.1091/mbc.E17-09-0561 |
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