MassARRAY-based simultaneous detection of hotspot somatic mutations and recurrent fusion genes in papillary thyroid carcinoma: the PTC-MA assay

PURPOSE: We exploited the MassARRAY (MA) genotyping platform to develop the “PTC-MA assay”, which allows the simultaneous detection of 13 hotspot mutations, in the BRAF, KRAS, NRAS, HRAS, TERT, AKT1, PIK3CA, and EIF1AX genes, and six recurrent genetic rearrangements, involving the RET and TRK genes...

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Detalles Bibliográficos
Autores principales: Pesenti, Chiara, Muzza, Marina, Colombo, Carla, Proverbio, Maria Carla, Farè, Claudia, Ferrero, Stefano, Miozzo, Monica, Fugazzola, Laura, Tabano, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Endocrine Methods and Techniques
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997117/
https://www.ncbi.nlm.nih.gov/pubmed/29214440
http://dx.doi.org/10.1007/s12020-017-1483-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997117/
https://www.ncbi.nlm.nih.gov/pubmed/29214440
http://dx.doi.org/10.1007/s12020-017-1483-2

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