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Droplet digital PCR is an accurate method to assess methylation status on FFPE samples

Most tissue samples available for cancer research are archived as formalin-fixed paraffin-embedded (FFPE) samples. However, the fixation process and the long storage duration lead to DNA fragmentation and hinder epigenome analysis. The use of droplet digital PCR (ddPCR) to detect DNA methylation has...

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Detalles Bibliográficos
Autores principales: Van Wesenbeeck, Liesbeth, Janssens, Leen, Meeuws, Hanne, Lagatie, Ole, Stuyver, Lieven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997148/
https://www.ncbi.nlm.nih.gov/pubmed/29527977
http://dx.doi.org/10.1080/15592294.2018.1448679