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Droplet digital PCR is an accurate method to assess methylation status on FFPE samples
Most tissue samples available for cancer research are archived as formalin-fixed paraffin-embedded (FFPE) samples. However, the fixation process and the long storage duration lead to DNA fragmentation and hinder epigenome analysis. The use of droplet digital PCR (ddPCR) to detect DNA methylation has...
Autores principales: | Van Wesenbeeck, Liesbeth, Janssens, Leen, Meeuws, Hanne, Lagatie, Ole, Stuyver, Lieven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997148/ https://www.ncbi.nlm.nih.gov/pubmed/29527977 http://dx.doi.org/10.1080/15592294.2018.1448679 |
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