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Spatial relationship between bone formation and mechanical stimulus within cortical bone: Combining 3D fluorochrome mapping and poroelastic finite element modelling

Bone is a dynamic tissue and adapts its architecture in response to biological and mechanical factors. Here we investigate how cortical bone formation is spatially controlled by the local mechanical environment in the murine tibia axial loading model (C57BL/6). We obtained 3D locations of new bone f...

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Detalles Bibliográficos
Autores principales: Carriero, A., Pereira, A.F., Wilson, A.J., Castagno, S., Javaheri, B., Pitsillides, A.A., Marenzana, M., Shefelbine, S.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997173/
https://www.ncbi.nlm.nih.gov/pubmed/29904646
http://dx.doi.org/10.1016/j.bonr.2018.02.003