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Identification of Drivers of Aneuploidy in Breast Tumors

Although aneuploidy is found in the majority of tumors, the degree of aneuploidy varies widely. It is unclear how cancer cells become aneuploid or how highly aneuploid tumors are different from those of more normal ploidy. We developed a simple computational method that measures the degree of aneupl...

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Detalles Bibliográficos
Autores principales: Pfister, Katherine, Pipka, Justyna L., Chiang, Colby, Liu, Yunxian, Clark, Royden A., Keller, Ray, Skoglund, Paul, Guertin, Michael J., Hall, Ira M., Stukenberg, P. Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997284/
https://www.ncbi.nlm.nih.gov/pubmed/29847804
http://dx.doi.org/10.1016/j.celrep.2018.04.102