Aerobic Glycolysis Is Essential for Normal Rod Function and Controls Secondary Cone Death in Retinitis Pigmentosa

Aerobic glycolysis accounts for ~80%–90% of glucose used by adult photoreceptors (PRs); yet, the importance of aerobic glycolysis for PR function or survival remains unclear. Here, we further established the role of aerobic glycolysis in murine rod and cone PRs. We show that loss of hexokinase-2 (HK...

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Detalles Bibliográficos
Autores principales: Petit, Lolita, Ma, Shan, Cipi, Joris, Cheng, Shun-Yun, Zieger, Marina, Hay, Nissim, Punzo, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997286/
https://www.ncbi.nlm.nih.gov/pubmed/29847794
http://dx.doi.org/10.1016/j.celrep.2018.04.111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997286/
https://www.ncbi.nlm.nih.gov/pubmed/29847794
http://dx.doi.org/10.1016/j.celrep.2018.04.111

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