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Oxaliplatin-induced changes in microbiota, TLR4+ cells and enhanced HMGB1 expression in the murine colon

Oxaliplatin is a platinum-based chemotherapeutic used for cancer treatment. Its use associates with peripheral neuropathies and chronic gastrointestinal side-effects. Oxaliplatin induces immunogenic cell death by provoking the presentation of damage associated molecular patterns. The damage associat...

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Detalles Bibliográficos
Autores principales: Stojanovska, Vanesa, McQuade, Rachel M., Fraser, Sarah, Prakash, Monica, Gondalia, Shakuntla, Stavely, Rhian, Palombo, Enzo, Apostolopoulos, Vasso, Sakkal, Samy, Nurgali, Kulmira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997344/
https://www.ncbi.nlm.nih.gov/pubmed/29894476
http://dx.doi.org/10.1371/journal.pone.0198359