Cargando…

Two functional indel polymorphisms in the promoter region of the Brahma gene (BRM) and disease risk and progression-free survival in colorectal cancer

BACKGROUND AND OBJECTIVE: The Brahma gene (BRM) encodes a catalytic ATPase subunit of the Switch/Sucrose non-fermentable (SWI/SNF) complex, which modulates gene expression and many important cellular processes. Two indel polymorphisms in the promoter region of BRM (BRM-741 and BRM-1321) are associat...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Yajun, Cheng, Dangxiao, Parfrey, Patrick, Liu, Geoffrey, Savas, Sevtap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997361/
https://www.ncbi.nlm.nih.gov/pubmed/29894502
http://dx.doi.org/10.1371/journal.pone.0198873