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Male mice with large inversions or deletions of X-chromosome palindrome arms are fertile and express their associated genes during post-meiosis

Large (>10 kb) palindromic sequences are enriched on mammalian sex chromosomes. In mice, these palindromes harbor gene families (≥2 gene copies) expressed exclusively in post-meiotic testicular germ cells, a time when most single-copy sex-linked genes are transcriptionally repressed. This observa...

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Detalles Bibliográficos
Autores principales: Kruger, Alyssa N., Ellison, Quinn, Brogley, Michele A., Gerlinger, Emma R., Mueller, Jacob L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997626/
https://www.ncbi.nlm.nih.gov/pubmed/29895860
http://dx.doi.org/10.1038/s41598-018-27360-x