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Male mice with large inversions or deletions of X-chromosome palindrome arms are fertile and express their associated genes during post-meiosis
Large (>10 kb) palindromic sequences are enriched on mammalian sex chromosomes. In mice, these palindromes harbor gene families (≥2 gene copies) expressed exclusively in post-meiotic testicular germ cells, a time when most single-copy sex-linked genes are transcriptionally repressed. This observa...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997626/ https://www.ncbi.nlm.nih.gov/pubmed/29895860 http://dx.doi.org/10.1038/s41598-018-27360-x |