An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness

The mechanical environment can influence cell behaviour, including changes to transcriptional and proteomic regulation, morphology and, in the case of stem cells, commitment to lineage. However, current tools for characterizing substrates’ mechanical properties, such as atomic force microscopy (AFM)...

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Detalles Bibliográficos
Autores principales: Galarza Torre, Asier, Shaw, Joshua E., Wood, Amber, Gilbert, Hamish T. J., Dobre, Oana, Genever, Paul, Brennan, Keith, Richardson, Stephen M., Swift, Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997644/
https://www.ncbi.nlm.nih.gov/pubmed/29895825
http://dx.doi.org/10.1038/s41598-018-27346-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997644/
https://www.ncbi.nlm.nih.gov/pubmed/29895825
http://dx.doi.org/10.1038/s41598-018-27346-9

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