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Metabolic Patterning on a Chip: Towards in vitro Liver Zonation of Primary Rat and Human Hepatocytes

An important number of healthy and diseased tissues shows spatial variations in their metabolic capacities across the tissue. The liver is a prime example of such heterogeneity where the gradual changes in various metabolic activities across the liver sinusoid is termed as “zonation” of the liver. H...

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Detalles Bibliográficos
Autores principales: Kang, Young Bok (Abraham), Eo, Jinsu, Mert, Safak, Yarmush, Martin L., Usta, O. Berk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997652/
https://www.ncbi.nlm.nih.gov/pubmed/29895900
http://dx.doi.org/10.1038/s41598-018-27179-6