Cargando…

Caspr1 is a host receptor for meningitis-causing Escherichia coli

Escherichia coli is the leading cause of neonatal Gram-negative bacterial meningitis, but the pathogenesis of E. coli meningitis remains elusive. E. coli penetration of the blood–brain barrier (BBB) is the critical step for development of meningitis. Here, we identify Caspr1, a single-pass transmemb...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Wei-Dong, Liu, Dong-Xin, Wei, Jia-Yi, Miao, Zi-Wei, Zhang, Ke, Su, Zheng-Kang, Zhang, Xue-Wei, Li, Qiang, Fang, Wen-Gang, Qin, Xiao-Xue, Shang, De-Shu, Li, Bo, Li, Qing-Chang, Cao, Liu, Kim, Kwang Sik, Chen, Yu-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997682/
https://www.ncbi.nlm.nih.gov/pubmed/29895952
http://dx.doi.org/10.1038/s41467-018-04637-3