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Universal response in the RKO colon cancer cell line to distinct antimitotic therapies

Both classic and newer antimitotics commonly induce a prolonged mitotic arrest in cell culture. During arrest, cells predominantly undergo one of two fates: cell death by apoptosis, or mitotic slippage and survival. To refine this binary description, a quantitative understanding of these cell respon...

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Detalles Bibliográficos
Autores principales: Lorz, Alexander, Botesteanu, Dana-Adriana, Levy, Doron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997697/
https://www.ncbi.nlm.nih.gov/pubmed/29895957
http://dx.doi.org/10.1038/s41598-018-27267-7